{"id":769,"date":"2021-05-17T10:21:10","date_gmt":"2021-05-17T02:21:10","guid":{"rendered":"http:\/\/www.wuchangsong.com\/?p=769"},"modified":"2021-05-17T10:21:10","modified_gmt":"2021-05-17T02:21:10","slug":"science%ef%bc%9a%e6%96%b0%e7%a0%94%e7%a9%b6%e6%8f%ad%e7%a4%bab1%e7%bb%86%e8%83%9e%e7%9a%84%e8%b5%b7%e6%ba%90","status":"publish","type":"post","link":"http:\/\/www.wuchangsong.com\/?p=769","title":{"rendered":"Science\uff1a\u65b0\u7814\u7a76\u63ed\u793aB1\u7ec6\u80de\u7684\u8d77\u6e90"},"content":{"rendered":"<p>\u5728\u4e00\u9879\u65b0\u7684\u7814\u7a76\u4e2d\uff0c\u5fb7\u56fd\u9a6c\u514b\u65af-\u5fb7\u5c14\u5e03\u5415\u514b\u5206\u5b50\u533b\u5b66\u4e2d\u5fc3\u7684Klaus Rajewsky\u6559\u6388\u53ca\u5176\u56e2\u961f\u62a5\u9053B1\u7ec6\u80de\u7684\u4ea7\u751f\u5e76\u4e0d\u9700\u8981\u4e0d\u540c\u7684\u7956\u7ec6\u80de\u3002\u76f8\u53cd\uff0c\u4ed6\u4eec\u7684\u5b9e\u9a8c\u8868\u660eB1\u5178\u578b\u7684B\u7ec6\u80de\u53d7\u4f53\uff08B1-typical B-cell 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\u8bf4\uff0c\u201c\u5f53\u6211\u4eec\u5c06\u5b83\u4eec\u79fb\u690d\u5230\u5c0f\u9f20\u4f53\u5185\u65f6\uff0c\u5b83\u4eec\u4f1a\u5f52\u5de2\u5230\u8eab\u4f53\u4e2d\u5929\u7136\u53d1\u73b0B1\u7ec6\u80de\u7684\u90a3\u4e9b\u90e8\u4f4d\u3002\u201d<\/p>\n<p>\u6b64\u5916\uff0c\u8fd9\u4e9b\u7ec6\u80de\u5f00\u59cb\u81ea\u53d1\u5730\u4ea7\u751f\u6297\u4f53\u3002Graf\u89e3\u91ca\u9053\uff0c\u201c\u8fd9\u4e5f\u662fB1\u7ec6\u80de\u7684\u5178\u578b\u7279\u5f81\u3002\u201d\u66f4\u91cd\u8981\u7684\u662f\uff0c\u4e00\u65e6B1\u5178\u578b\u7684B\u7ec6\u80de\u53d7\u4f53\u5728B2\u7ec6\u80de\u8868\u9762\u4e0a\u8868\u8fbe\uff0c\u8fd9\u4e9b\u7ec6\u80de\u5728\u4e00\u5230\u4e24\u5468\u7684\u65f6\u95f4\u5185\u5f00\u59cb\u5927\u91cf\u589e\u6b96\u3002\u8fd9\u4e0eB1\u7ec6\u80de\u5728\u65e9\u671f\u9636\u6bb5\u7684\u81ea\u7136\u53d1\u80b2\u975e\u5e38\u76f8\u4f3c&#8212;\u8fd9\u4e2a\u8fc7\u7a0b\u5f88\u5c11\u88ab\u7814\u7a76\u8fc7\u3002<\/p>\n<p><strong>\u65f7\u65e5\u6301\u4e45\u7684\u4e89\u8bba\u5373\u5c06\u7ed3\u675f<\/strong><\/p>\n<p>\u5728\u8fd9\u9879\u7814\u7a76\u7684\u540e\u671f\uff0cGraf\u6d4b\u91cf\u4e86\u8fd9\u4e9b\u7ecf\u8fc7\u64cd\u7eb5\u7684B2\u7ec6\u80de\u4e2d\u6570\u5343\u4e2a\u57fa\u56e0\u7684\u6d3b\u6027\u3002Graf \u62a5\u9053\uff0c\u201c\u5728\u8fd9\u9879\u7814\u7a76\u4e2d\uff0c\u6211\u4eec\u53d1\u73b0\u8fd9\u4e9b\u76f8\u540c\u7684\u57fa\u56e0\u5728\u8fd9\u4e9b\u7ec6\u80de\u4e2d\u548c\u6b63\u5e38\u7684B1\u7ec6\u80de\u4e2d\u90fd\u662f\u6709\u6d3b\u6027\u7684\u3002\u201d<\/p>\n<p>Graf\u671f\u5f85\u8fd9\u9879\u65b0\u7684\u7814\u7a76\u5c06\u8ba9\u514d\u75ab\u5b66\u5bb6\u76f8\u4fe1B1\u7ec6\u80de\u662f\u7531\u4e8e\u5b83\u4eec\u7684B\u7ec6\u80de\u53d7\u4f53\u7684\u7279\u5f02\u6027\u800c\u51fa\u73b0\u7684\u3002\uff08\u751f\u7269\u8c37 Bioon.com\uff09<\/p>\n<p>\u8f6c\u8f7d\u81ea\uff1a<a href=\"http:\/\/news.bioon.com\/article\/6734027.html\">http:\/\/news.bioon.com\/article\/6734027.html<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u5728\u4e00\u9879\u65b0\u7684\u7814\u7a76\u4e2d\uff0c\u5fb7\u56fd\u9a6c\u514b\u65af-\u5fb7\u5c14\u5e03\u5415\u514b\u5206\u5b50\u533b\u5b66\u4e2d\u5fc3\u7684Klaus Rajewsky\u6559\u6388\u53ca\u5176\u56e2\u961f\u62a5\u9053B1\u7ec6\u80de\u7684\u4ea7\u751f\u5e76\u4e0d\u9700\u8981\u4e0d\u540c\u7684\u7956\u7ec6\u80de\u3002\u76f8\u53cd\uff0c\u4ed6\u4eec\u7684\u5b9e\u9a8c\u8868\u660eB1\u5178\u578b\u7684B\u7ec6\u80de\u53d7\u4f53\uff08B1-typical B-cell receptor\uff09\u80fd\u591f\u5c06B2\u7ec6\u80de\u91cd\u7f16\u7a0b\u4e3aB1\u7ec6\u80de\uff0c\u8fd9\u8868\u660eB1\u7ec6\u80de\u662f\u7531\u4e8e\u5b83\u4eec\u7684\u7279\u6b8aB\u7ec6\u80de\u53d7\u4f53\u800c\u51fa\u73b0\u7684\u3002\u8fd9\u9879\u7814\u7a76\u53ef\u80fd\u4f1a\u89e3\u51b3\u4e00\u9879\u6301\u7eed\u4e86\u51e0\u5341\u5e74\u7684\u514d\u75ab\u5b66\u4e89\u8bba\u3002\u76f8\u5173\u7814\u7a76\u7ed3\u679c\u53d1\u8868\u57282019\u5e742\u670815\u65e5\u7684Science\u671f\u520a\u4e0a\uff0c\u8bba\u6587\u6807\u9898\u4e3a\u201cBCR-dependent lineage plasticity in mature B 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